Additional features of the pathogen may also contribute to whether excessive transmission occurs, such as viral strain characteristics, viral load, or the presence of coinfecting organisms.
In summary, this study provides useful epidemiological data on the features of the pathogen compositions of HFMD as well as clinical characteristics differing in enterovirus genotypes in Shanghai, China.
SEM did not reveal any features of the pathogen, and inoculated SM strain was susceptible to imipenem and cefoperazone sulbactam only.
Instead, the answer is likely to be more complex, and here we have presented several factors that could play significant roles, including zoonotic transmission of M. tuberculosis and genetic features of the pathogen and/or the host population.
The features of the pathogen, risk factors and severity of candidemia in elderly patients may differ from that in younger adults and might be associated with worse prognosis [ 14].
These definitions, however, do not take into account the role of host susceptibility to infection; instead, they note only those features of the pathogen which are responsible for disease development.
Our study shows that one can pre-determine key features of the pathogen-species specific immune response of the pbMEC by selecting the specific stimulation condition.
The observation that a number of pathogenesis-related (PR) genes are induced during leaf senescence has lead to the suggestion that the senescence program might have incorporated features of the pathogen-defense response to protect the senescing leaf against opportunistic pathogens [ 73].
Hence, we discovered a new feature of the opportunistic pathogen S. marcescens – the invasiveness in various human epithelial cell lines.
Although all these factors contribute to Mtb persistence within the macrophage, one recurring and highly important feature of this pathogen is inhibition of normal phagosome maturation process, thereby abrogating physical fusion of phagosome with lysosomes and ultimately protecting the bacterium from a bactericidal environment [7], [8], [9].
