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Thus it would seem that the ' % >2' metric captures some feature of TCS organisation distinct from the ' number of TCS genes', or the ' number of genes/domains per focus'.
In vitro studies have shown that, as a key feature of TCs, the increment of androgen production was driven by LH in a dose-dependent manner [ 5, 11, 12].
This correlation has been previously pointed out as a common feature of TCS [ 4, 14, 15] and led to Grebe and Stock to propose that many HKs and their cognate RRs have evolved as integral units [ 14], a view in agreement with the coevolution model [ 4].
Similar(57)
In this study, we have introduced a new approach to identify new members of known classes of ncRNAs based on the features of TCs corresponding to known ncRNAs.
The characteristic features of TCs overlapping with known ncRNAs were used to predict 7 and 26 box H/ACA and box C/D snoRNA candidates, respectively, in addition to one snRNA and many novel unclassified ncRNA candidates, a substantial fraction of which were experimentally validated.
The structural and functional features of TC-element-containing genes were distinct from those of TATA-box- or TATA-variant-containing genes.
The key feature of the TC considered here is that it has a fixed-term duration and that it cannot be renewed using the same worker.
Their data demonstrated that the differential expression of subset of genes in chromosomes 17 and 18 were unique features of pulmonary TCs, and they might be used as biomarkers to distinguish TCs from the other type of cells.
These analyses reveal two important features: variability of TC formation location and moving tracks.
In addition, thyroid surgery was also recommended for patients with two non-diagnostic or benign FNABs with two or more US features suggestive of TC (irregular margins, microcalcifications, hypoechoic pattern) or increased size.
The specific up-regulated genes, i.e. Mapk14, Trem2, MCFD2 and Dpysl3, and specific down-regulated genes, i.e. E4F1 and PDCD2, in chromosome 17 and 18 made us have a deeper insight into biological features and functions of TCs.
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