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Reduced NAA-levels in the NAWM of patients with MS is a feature of progression.
It is well known that chronic low-grade inflammation is a common feature of progression of NAFLD.
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However, relatively little is known about whether RTT mouse models recapitulate the unique features of progression, regression and stabilization that define the human disease.
As previously described, hypoxia induced the stabilization and accumulation of HIF-1α protein which is a feature of metastatic progression in various cancers79.
Despite the widespread belief that neuropsychological decline is a cardinal feature of the progression from the premorbid stage to the chronic form of schizophrenia, few longitudinal studies have examined change in neuropsychological functioning from before to after illness onset.
In tumors, a shift towards a more mesenchymal phenotype is a common feature of disease progression for which Endo180 could serve as a surrogate marker.
For this reason, we hypothesized that if MAPK phosphorylation of HIV proteins was an essential feature of the progression of HIV infection, then MAPK docking sites along HIV proteins would be strain independent.
We detected the same trend from an independent psoriasis gene expression study, indicating that density-dependent, genome-wide gene expression changes is a salient feature of psoriasis progression (Figure S8B) [21].
Impaired glucose metabolism is a key feature of AD progression.
Excessive immune activation as indicated by CD38 expression is a characteristic feature of HIV progression.
Thus, the MYC pathway is a putative key feature of metastatic progression [ 59].
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