Sentence examples for feature of multiple sclerosis from inspiring English sources
Relapses are the most florid clinical feature of multiple sclerosis.
The accumulation of activated microglia and blood-derived macrophages in the central nervous system (CNS) is an early and persistent feature of multiple sclerosis (MS).
The absence of demyelinating or axopathic autoantibodies in patients with other neurological diseases suggests they are a specific feature of multiple sclerosis.
HDIT/AHCT may be more effective in patients with less advanced relapsing/remitting MS. Inflammation of the central nervous system (CNS) is a prominent feature of multiple sclerosis (MS).
Brain atrophy and cognitive dysfunction are neurodegenerative features of Multiple Sclerosis (MS).
Our PTx+EAE model reflects some key features of multiple sclerosis lesions and provides a novel approach to study the mechanism responsible for the localization of demyelinating lesion in the brain versus spinal cord.
In addition, there is a wide spectrum of pathological features of multiple sclerosis lesions, depending upon the type and severity of the disease as well as the stage of the lesions (Lucchinetti et al., 2000; Lassmann et al., 2007).
In particular, EAE (experimental autoimmune encephalomyelitis), a mouse disease model that exhibits the clinical and pathological features of multiple sclerosis, is alleviated by AMPA and kainate receptor antagonists (Pitt et al., 2000; Smith et al., 2000).
Experimental autoimmune encephalomyelitis in the Biozzi ABH mouse recapitulates the clinical and pathological features of multiple sclerosis including relapse-remitting episodes with inflammatory mediated demyelination and progressive disability with neurodegeneration.
Importantly, sustained activation of P2X7 receptors in vivo causes lesions that are reminiscent of the major features of multiple sclerosis plaques, and treatment of chronic EAE with P2X7 antagonists reduces demyelination and ameliorates the associated neurological symptoms (Matute et al., 2007b).
