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Table 2 Final agreed criteria for prioritisation 1. Answerability/feasibility: it will be feasible to answer this research question in a humanitarian context.
In this review, we show that the advent of next-generation sequencing technologies and the growing use of genomic approaches make it increasingly feasible to answer these fundamental questions using ecological and evolutionary 'non-model' populations of vertebrates in nature.
Biomedical questions should be applicable to human clinical studies and more feasible to answer with PET imaging versus other, possibly less resource-intensive, tools.
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To show how this is feasible we try to answer three basic questions: How cognitive mapping can support decision-making?
The matrix indicators (list of activities) are selected on the basis that they are comprehensive whilst also feasible to be answered based upon written documents in the public domain.
"But sometimes, it's just not feasible to do it".
Although they provide lower levels of evidence, these studies are important when it is not feasible to conduct RCTs to answer the questions posed.
Plummeting sequencing costs, combined with increasing throughput and read lengths, should make sequencing whole mitochondrial genomes in many individuals feasible, providing rich opportunities to answer these questions in the future.
In this first study the authors decided to deploy the SeptiFast® blood pathogen test in full accordance to its instruction to answer the question whether it is feasible in urine samples.
Questions need to be sufficiently important (i.e., address a large part of the epidemic) to justify the in-depth search for data, to be actionable (i.e., that an answer will result in public health decisions), to have sufficient data available to answer the question and to be feasible given time and resource constraints.
To understand the reasons for this difference and to answer the question of whether it is feasible to design tailor-made chaperones, we investigated one of the most prominent bacterial chaperones, the GroEL/ES ring complex.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com