Recently, a phase II clinical trial in hepatocellular carcinoma (HCC) has suggested that the combination of sorafenib and 5-fluorouracil (5-FU) is feasible and side effects are manageable.
Inter-molecular H-bonds are deemed feasible if side chain conformations sampled from the MD in the absence of DNA are within an empirical 4 Å distance threshold of the DNA acceptor/donor.
DR-management is feasible in the side position in term infants.
"Although I want it to be debated, to test whether this solution is feasible, looking for side effects is very essential," he says.
In hepatic organ dysfunction, dose reductions to lower doses seem to be feasible without additional side effects.
Consequently, finer-scale localization of QTL in salmon is more feasible from female side using larger number of markers.
The protocol used for treatment monitoring was feasible while no side effects of RT could be observed during the follow up period.
Recently, a phase II clinical trial has suggested that the combination of sorafenib and 5-fluorouracil is feasible, and the side effects are manageable for patients carefully selected for liver function and performance status [ 12].
In the prospective randomized Xtravent-study, Bein et al. [ 42] demonstrated that use of very low tidal volumes (3 ml/kg PBW) combined with extracorporeal elimination of CO2 was feasible without major side effects and might be beneficial in the treatment of patients with severe ARDS.
At the same time, it is feasible to introduce side-chain flexibility on a limited number of residues as our results show that five flexible side chains account for 90% of the observed cases.
