Sentence examples for feasible compounds from inspiring English sources

Although, these molecules may have different physicochemical properties, the initial fragments are procured from biologically active and synthetically feasible compounds.

Furthermore, we track the connectivity between individual fragments, so that chemically feasible compounds can be synthesized using a graph-based algorithm.

Computer-aided product design requires the generation of feasible compounds and the prediction of solution and pure component properties by group contribution methods.

Fig. 1 The computational strategy for rational design of A1R/A2AR PDE10A multi-target ligands started with a focused chemical space consisting of known actives of A1R, A2AR and PDE10A, and formed new synthetically feasible compounds which were subjected to target prediction and docking for synthesis and pharmacological evaluation.

Finally, all of feasible compounds in NCI database were selected by using ligand-based virtual screening.

All of feasible compounds in NCI database were selected in this work.

DR approach [20] is based on the assumption that synthetically feasible compound lies in rather dense part of chemical space (i.e., it has many structurally similar neighbors), while unfeasible compound occupies a sparse chemical space region.

Thus, it is feasible that compounds that are active against the bovine parasite will also affect the human parasite, O. volvulus.

Thus, it is essential to use synthetically feasible bioactive compounds as the source in order to generate molecules with similar chemical and pharmacological profiles.

As such, the proposed method is feasible for compound flooding in high-temperature reservoirs.

The good correlations between k 25 (Fig. 8) and E a (Fig. 11) determined by non-isothermal vs. isothermal and the comparable binning classification results by the two methods (Tables 6 and 7) indicate that the LNISO method is feasible for compound binning.