Feasibility of localized outbreak detection is demonstrated without swamping true signals by excessive false alarms.
In the prospective study, we show the feasibility of detecting outbreaks in near real time, as well as improved resolution, of the method that enables detection of numerous potential outbreak clusters that would likely go undetected by PFGE.
This is a first national operational research project with objectives to study the feasibility of implementing modern dengue outbreak detection methodologies and to evaluate these methods at better alternatives to the current outbreak detection method (median-5-years) in Thailand.
We performed a pilot study to determine the feasibility of using bacterial WGS to differentiate outbreak from non-outbreak isolates collected during an outbreak of Legionnaires' disease.
To guide health authorities regarding OCV use during complex emergencies, WHO proposes a 3-step predictive risk assessment approach, which considers 1) the risk for cholera outbreak, 2) outbreak containment capacity, and 3) the feasibility of conducting a mass vaccination campaign (14 ).
We have demonstrated the feasibility of using rapid WGS to investigate an outbreak of Legionnaires' disease.
To demonstrate the feasibility of this approach in elucidating the cause of outbreaks from hitherto novel or unknown viruses, we generated a modified NT database from which all sequences corresponding to the Orthomyxoviridae family had been removed (Fig. 8A).
Wrong estimations of epidemic velocities are for inefficient outbreak reporting systems during the course of epidemics which makes very difficulty the detection of outbreak sources, attribution of outbreaks to food and/or infected individuals, and prediction of outbreak spread.
Here, we have demonstrated the feasibility of using WGS to perform an investigation of a Legionella outbreak.
The aim of this pilot study was to determine the feasibility of using bacterial WGS for the investigation of a previous Legionella outbreak.
