Sentence examples for feasibility of editing from inspiring English sources

Our aim here was to demonstrate the feasibility of editing a plant genome by precisely modifying a defined target DNA motif.

The aim of this study was to demonstrate the feasibility of editing the barley genome by precisely modifying a defined target DNA sequence resulting in a predicted alteration of gene function.

In 2013, two groups from MIT and Harvard demonstrated the feasibility of genome editing of human cells using the CRISPR/Cas9 system (Cong et al., 2013; Mali et al., 2013b).

Further evaluation of the intervention, including testing the feasibility of the editing process, is needed.

In the past years, a number of proof of principle studies have validated the feasibility of epigenetic editing in reporter plasmids, viral DNA, and endogenous targets (reviewed in [ 18]) and paved the way towards more comprehensive studies.

To test the feasibility of genome editing and the creation of knock-in alleles in zebrafish, we chose the alb phenotype as an easy and quick visible read-out that is independent of PCR methods, which, in our hands, are error prone and often produce false positive and false negative results.

This study, therefore, proves the feasibility of successfully performing gene editing at the FXN locus.

These results demonstrate the feasibility of RNA-programmed genome editing in human cells.

Taken together, our work demonstrates the feasibility of generating point mutations in mouse by base editing, and underscores the need to carefully optimize base editing systems in order to eliminate proximal-site deamination.

EM: analyzing of data, editing.

Taken together, these results clearly indicate the feasibility of repairing HBB −28 (A>G) in human cells in situ by base editing.