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In the next step, BNICE screens out all possible pathways for thermodynamic feasibility based on the Gibbs free energies of the reaction and selects feasible novel thermodynamic pathways [ 57].
The thermodynamic evaluation of reaction feasibility, based on the standard Gibbs energies of reaction, faces difficulties when, instead of isolated reactions, we are examining whole pathways.
AIM 1: To compare robotic and laparoscopic surgery to the open approach, in terms of safety and feasibility, based on the intraoperative and postoperative outcomes.
Our intention is to test the safety and feasibility based on the incidence of NCI-CTCAE °3/4 side effects and/or discontinuation due to any reason.
However, there is increased early toxicity, a possibility in reducing RIF to a bacteriostatic agent due to low concentrations within granulomas, and limited feasibility based on the high carrier loading that would be required.
The in- and exclusion criteria are found in Table 1.> Primary endpoint is safety and feasibility based on the incidence of NCI-CTCAE °3/4 side effects and/or discontinuation due to any reason.
Similar(54)
The primary end point was the tolerance and feasibility based on (i) the maximal tolerated dose (MTD) defined as the highest DL tested with <2 dose-limiting toxicity (DLT), observed in a maximum of nine patients (in a 3+3+3 dose escalation design) and (ii) the maximum administered dose (MAD) defined as the highest DL tested with at least 2 DLT (⩾2) out of three to six patients.
Depending on how much each instance effectively costs the business, we see two distinct regions of feasibility based on convexity of the curves.
The repair principle used in this paper has been proposed by Marian et al. (2000, 2006; Marian 2003) as follows: Every gene after the cut point must be checked against the feasibility based on recorded information about all of the previous assembly operations, not just the adjacent one.
Two feasibility conditions are formulated that make it possible to investigate feasibility based on information coming solely from the distillation line map along with the binodal curve of the ternary mixture.
The primary end point was feasibility based on maximal tolerated dose (MTD) and maximum administered dose (MAD).
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