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Fc receptor.
FcγRIIB, the only inhibitory IgG Fc receptor, functions to suppress the hyper-activation of immune cells.
This arises from IgG interaction with the neonatal Fc receptor, FcRn.
The resultant sc Fc 2 candidate preserved the neonatal Fc receptor (FcRn) binding.
The "hypothesized" Brambell receptor, later called neonatal Fc receptor (FcRn), was cloned in 1989 (Simister & Mostov, 1989).
The neonatal Fc receptor (FcRn) is a heterodimer that comprises transmembrane α chains and β2-microglubulin (β2m).
Similar(15)
Immune thrombocytopenia depends upon Fc receptor-mediated phagocytosis that involves signaling through the SH2 tyrosine kinase, Syk.
The Fc receptor-expressing monocytic-like U-937 cell line was grown in RMPI-1640 medium.
These results suggested an Fc receptor-independent mechanism for IgG-SPIO cell entry.
A recent study suggested that Fc receptor-mediated protection is important in MSP1-induced immunity [29].
The proportion of Fc receptor-positive cells also increase (from ∼20% to ∼50%) during differentiation with retinoic acid [4].
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