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It is debatable whether superior TS represents a favourable treatment effect or merely tumour biology.
Negative values for differences between groups represent a favourable treatment effect.
Additionally, a favourable treatment effect was observed across the full distribution of change from baseline to 1 year in FVC % pred (figure 1b).
A recent systematic review of land-based exercise for hip OA combining the results of five clinical trials demonstrated a small favourable treatment effect for pain, but no benefit in terms of self-reported physical function [ 5].
The MGMT status could only be assessed in 36% of the patients and was shown to be predictive of a favourable treatment effect in patients receiving TMZ chemotherapy (Hegi et al, 2005).
The NNT determines the number of patients that need to be treated in order to obtain the benefit of interest in one additional patient (small NNTs indicate a favourable treatment effect). 2 Additionally, the predictive value of MCIDs can be evaluated by examining whether achieving improvements ≥MCID earlier with active treatment result in better longer term clinical outcomes.
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However, most of the published trials do not have sufficient power to identify favourable treatment effects.
Furthermore, these more favourable treatment effects were greatest for the 1.8 mg dose of liraglutide.
12 15 These favourable treatment effects consistently occurred with reduced tissue myeloperoxidase content in keeping with less neutrophil recruitment.
Several studies with favourable treatment effects utilised interventions that targeted specific needs of carers such as therapy for sleep deprivation and training in problem-solving skills.
Reference category is favourable treatment outcome.
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