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In the reaction of morpholinone with hex-5-enal, the most favourable transition state is shown to be the anti-addition to the E-ylide (Eact ∼12 kcal/mol by HF/3-21G).
In the example described below we focus on the properties of the true positive binding funnel and calculate mean first-passage times between distinct conformational states within the funnel, i.e. we are interested in finding the favourable transition path from the top to the bottom of the binding funnel.
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The quantum mechanical calculations suggest a favourable phase transition into a RS structure with different transition pressure for 3C SiC.
Alternating purine pyrimidine patterns can under favourable conditions promote transitions to the Z-DNA conformation, while oligopurine/oligopyrimidine runs promote formation of A-DNA or triple-stranded H-DNA.
This is consistent with the earlier hypothesis that favourable dietary changes during transition were the main reason for the sharp decline in cardiovascular mortality.
> -wrap-foot> is is worthwhile to note that we are not aiming to predict accurately every site in the genome that is likely to undergo a conformational transition under favourable conditions.
Given this limitation, we selected the sequence patterns to be approximately representative of the sequences known to undergo the specific structural transitions under favourable conditions.
It is time to capitalise on the global policy environment, which is becoming more favourable to action on health transition in Africa, and implement a research agenda for health transition.
It is time to capitalise on the global policy environment becoming more favourable to action on health transition in Africa [ 29, 30] and implement a research agenda on health transition which builds on the well established research agenda for communicable diseases such as HIV [ 31] and malaria [ 32] and on recent contributions to the agenda for NCDs [ 16].
Individual changes in MAU and WSAS categories between ages 14 and 19 were classified into a CHANGE score: 1) better (transition to a more favourable category), 2) stable (same category) and 3) worse (transition to a less favourable category).
The pressure applied to the reacting system also may be significant, partly because it has an effect on concentration and partly because mechanisms involving closely associated transition states become more favourable at high pressures.
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