AREG mRNA had a favourable predictive significance in wild type cases only, whereas EREG mRNA preserved its significance in wild type as well as in mutant cases.
A similar favourable prognostic significance was assigned to Sox11 expression in ovarian carcinoma in terms of recurrence-free survival (Brennan et al, 2009; Sernbo et al, 2011), whereas in mantle cell lymphomas its prognostic significance has been disputed (Ek et al, 2008).
The favourable prognostic significance of the presence of tumour-infiltrating CD8+ T cells was previously reported in a variety of cancers, including colorectal cancer, oesophageal cancer, pancreatic cancer, bile duct cancer and gallbladder cancer (Naito et al, 1998; Nakano et al, 2001; Schumacher et al, 2001; Cho et al, 2003; Nakakubo et al, 2003; Oshikiri et al, 2003; Fukunaga et al, 2004).
Better OS and TTP in the group of super mobilisers were also observed across the ISS stages, with the favourable effect reaching significance (P=0.0039 and P=0.011) for patients with ISS stage III at diagnosis (data not shown).
The Concert for Bangladesh is continually viewed in a highly favourable light, its cultural significance seemingly increased with the passing decades.
We discuss the most radically cosmopolitan theory of justice first, working through to the conception most clearly favourable to foregrounding the normative significance of national borders.
Although the difference in S-100 levels of MTH patients with adverse or favourable neurological outcome reached statistical significance, it did not in NT patients.
Our observation presents additional evidence for the prognostic significance of PTEN aberration on favourable outcome in endometrial carcinoma, further providing significant implications for the management of the disease including molecular targeted therapies.
In conclusion, our data revealed the clinicopathological significance of MUC5B as a favourable prognostic factor in resected EGFR mutant NSCLC.
