Sentence examples for favourable interaction with from inspiring English sources

How can the favourable interaction with a relatively rigid, thermally-insulating infill be incorporated in the design equations?

When this study was developed, gemcitabine had shown significant activity in metastatic breast cancer, and there was evidence of a favourable interaction with paclitaxel.

This suggests an unusual insertion regiochemistry, which the authors suggest is a result of a favourable interaction with the proximate metal centre as is depicted in Fig. 14 [176] 176].

As mentioned above, NPs below 5 nm are often used for radiosensitisation purposes due to the relatively rapid elimination from the body, good uptake, and favourable interaction with radiation, but at these sizes AuNPs can become chemically reactive (Alkilany and Murphy 2010; Ionita et al. 2007; Zhang et al. 2003; Pan et al. 2009; Xia et al. 2006).

In addition, the likely protonation of one of the piperazine ring nitrogen atoms of PBTZ169 could generate a favourable interaction with two negatively charged residues, namely Asp318 and Glu322, present in the disordered loop (residues 314-328) lovered over the active site.

Furthermore, Leu941 favoured binding to H4K20me3 peptide by forming favourable interactions with the receptor residues.

RanBP1 disassembles export complexes by causing the Ran-interacting HEAT-9 loop to switch from an "outward" conformation that promotes favourable interactions with Ran (red loop in Figure 6A) to an "inward" conformation (blue loop) that induces a constriction of the NES-binding groove and consequent NES release [33].

In addition, the conformational flexibility around the aryl-aryl single bond allows the PBH to adopt its structure in order to obtain the most favourable interactions with other chemical species, thus achieving high biological activity [17].

Crystal structures of the enzyme inhibitor complexes showed that the nitrile warhead inhibits 3CLpro by forming a covalent bond with the catalytic Cys145 residue, while the AVLQ peptide forms a number of favourable interactions with the S1 S4 substrate-binding pockets.

The introduction of a 2-phenylimino moiety onto the 4-thiazolidinone ring was designed to enhance the inhibitor/enzyme affinity by means of further favourable interactions with residues of the active site and the surrounding loops.

This evidence suggests that methyl and lysyl groups located in the positiontiof of ACE inhibitors can form favourable interactions with the S1' sub-site of the C-terminal dofain of sACE. Figure 4 Comparison of the S1' sub-site residues which bind the lysyl group of lisinopril.