Exact(28)
Carriers of parkin mutations have a more favourable disease course compared to sporadic PD patients: although onset is generally earlier, disease progression is significantly slower and the response to dopaminergic treatment better than in sporadic PD [18], [19].
Favourable disease sites include the orbit or non-parameningeal head and neck sites.
Early intervention in RA is associated with a more favourable disease course [ 1, 2].
These biological features were not linked to favourable disease evolution, but this result must be interpreted cautiously in elderly patients.
Additionally, patients who had a favourable disease stage (stage I) tended to refuse the recommended therapy (P=0.0546).
Four patients achieved favourable disease responses (two patients had partial responses and two had minor responses) (Jayson et al, 1995).
Similar(32)
FGFR4 overexpression was associated with less favourable disease-specific survival (P<0.006, Figure 4A).
On the contrary, increased expression of ALDH1 in ovarian cancer correlates with more favourable disease-free and overall survival [ 18].
p16 overexpression was an independent indicator of a favourable disease-free survival, which is in line with other reports (Mellin et al, 2000).
Moreover increased MEK5 and ERK5 expression correlates with presence of bony metastases and less favourable disease-specific survival (Mehta et al, 2003).
Importantly, patients with completely resected types B2, B3 and C and adjuvant radiotherapy had more favourable disease-free and overall survival as compared with those without adjuvant radiotherapy.
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