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The application of this equation ensures that even an area with a relatively high human population density (class 1) would retain a high probability to harbour flat-headed cats if both the mean probability predicted by the MaxEnt model and its land cover class are favourable (class 3 or 4).
Applied to these samples, the seven-gene OPM defined a 'Favourable' class (n=187; 51%) and an 'Unfavourable' class (n=179; 49%) that strongly correlated with survival.
However, the most unfavourable class contains only 2 patients and the most favourable class only 7. For the score developed by Rades et al., the difference between the 2 unfavourable classes is not statistically significant either.
However, the rate of clinical complete response (CCR) was higher in the 'Favourable' class than in the 'Unfavourable' class (82 vs 46%), suggesting that the prognostic value of the OPM might be partly related to some predictive value for response to chemotherapy.
The 'Favourable' class contained 121 of the 194 alive patients and the 'Unfavourable' class contained 106 of the 172 deceased patients (Se=61.6%, Sp=62.4%, odd ratio=2.7, 95% CI=1.7 4.2; P=6.1E-06, Fisher's exact test), thus confirming the prognostic value of our OPM in a large and independent data set.
Once the best model was defined (OPM), a prediction score, defined by a Cox resulting linear function, was then calculated for each sample, thus defining two classes: the 'Unfavourable' class with a positive score and the 'Favourable' class with a negative score.
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As shown in Figure 3, the difference between the 2 favourable classes and the low intermediate group is not statistically significant.
The favourable course and his form.
When looking at the new graded prognostic assessment (GPA) score, we discovered that only 5 of our patients belonged to the 2 most favourable GPA classes.
It is generally agreed that children who breastfeed are more intelligent; however, debate remains whether this is a causal relationship or merely an association with favourable parental socioeconomic class and IQ.
Five-year OS was 57 and 27% for the predicted 'Favourable' and 'Unfavourable' classes, respectively.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com