As a result intra- and extracellular events occur that favour malignant transformation.
It is indeed well known that tumour cells displaying the Warburg effect become addicted to high glucose influxes, and that enhancing aerobic glycolysis can favour tumoural transformation.
Therefore, in presence of amastigotes, arg2 could favour arginine transformation into ornithine, the latter being catalyzed in turn by odc1 to generate putrescine (Fig. 4).
Furthermore, it influences the gaseous products' distribution by increasing H2 yield and not favouring the transformation of CO2 in CO.
Our finding that induction of DNA damage by CDT is accompanied by the concomitant activation of survival signals suggests that chronic infection with CDT producing bacteria may promote genomic instability and favour malignant transformation.
Displacive transformation appears to favour certain of the crystallographically equivalent variants and so gives a stronger texture than purely diffusional transformation.
After testing quadratic and logarithmic specifications, both education and per capita household expenditure favoured a logarithmic transformation.
An altered microenvironment may even rupture the homeostasis and favour the early steps of transformation (Raaijmakers et al, 2010).
The variant selection occurring during the transformation of the retained beta appears to favour a common orientation with the surrounding primary alpha grains, contributing to the size of the macrozones and therefore to the extent of the observed faceted regions.
(C) DNA mutations that allow cancer cells to accumulate genetic changes that favour selection towards chemoresistance [ 53]: this predisposition towards transformation makes cancer cells more resistant to chemotherapy.
