Statistical analysis of inhibition of both wild-type InhA and InhA (S94A) by pyridomycin favours a model of competitive inhibition with NADH as indicated by similar y-axis intercepts on Lineweaver Burk plots (Fig 4).
Rather than incomplete lineage sorting, MDIV favours a model of recent divergence between populations in Morocco and Tunisia (t ~ 150 KYA, Table 1), associated with weak but non-null gene flow (M ~ 0.15, see Additional file 4d).
These findings imply that Notch activity in neural progenitors is not restricted to a specific cell cycle phase and favour a model in which activation of Notch during neurogenesis is a random event, depending on chance encounters with ligand-expressing newborn neurons, while they are still in the ventricular zone of the neural tube.
The result is encouraging for those who favour 'opt out' as a model of consent.
To solve this signalling conundrum, we favour a model in which the association of Fyn and M2 will entail two independent, and mechanistically separable steps.
Taken together, these observations favour a model in which the major site of Mimivirus DNA replication is the cytoplasmic VF, and further suggest that there is a relationship between the two different structures during the replication cycle.
We favour a model where TM1 of the nascent TASK-1 chain transiently resides in a Sec61-enabled dynamic equilibrium such that the synthesis of additional polypeptide promotes the acquisition of its native orientation.
Instead, we favour a model based on interruption of histone recycling.
Although the determination of the optimal number of classes favoured a model with four classes, the two class model was selected on a model interpretability basis (see online supplementary table S4).
Those who favour a medical model of health can be described as realists, as they consider that health and disease are ubiquitous features of the natural world and draw upon descriptive definitions of health which are based upon biological function (Boorse, 1975).
