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Functional studies on mucus cell differentiation are still lacking, but it has been shown that the expression pattern of pCLCA1, the porcine ortholog to hCLCA1 and to mCLCA3, is virtually identical with that of hCLCA1, supporting the pig as the favored translational model (Plog et al. 2009).
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For this, a block matching algorithm employing a modified matching criterion is used [9]; the modified criterion adds weights to the MAD criterion to favor translational motion vectors closer to the block center to regularize the translational motion field.
Were transcription of the pre-miRNA to remain constant, preferential accumulation of the star strand could favor translational de-repression due to loss of the corresponding strand or inhibition of a distinct set of targets.
With scientific disciplines presently shifting in ways that favor the translational value of research, fundamental enzymology queries into enzyme function and catalysis still present important potential for discovery.
The large animal models are favored at the translational stage of the investigation, as they are anatomically and physiologically more proximal to humans, and can be implanted with various devices; however, they are expensive and less amenable to genetic manipulations.
Furthermore, the existence of translational competition favoring the translation of milk protein transcripts was inferred from the combined dataset.
Moreover, selection for translational accuracy favors translation with lower misincorporation rates of codons for functionally important amino acid residues, and thus, conserved amino acid residues should be more highly biased than others [ 10].
He and others honored by the Lasker Foundation asserted that amid dwindling federal research budgets, support for the conduct of basic science is being shunted aside in favor of "translational" work -- biomedical research directly related to the development of treatments and medicines.
This rapid expansion favors robust translational inquiry to utilize these cells in cellular therapy.
These also yield strong evidence in favor of translational activity by antisense tRNAs.
Since viral proteins themselves are often translated via IRESes, expression of these proteases favors viral protein translation and dramatically decreases translational activity of the host cell.
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