Sentence examples for favored orientation from inspiring English sources

Finally, the heme was modeled in the A orientation, which was shown to be the thermodynamically favored orientation for both NP7 and Met-NP7 Δ1 3). Met-NP7 Δ1 3

More importantly, the predicted N-dealkylation binding poses also suggested a crucial role of the 4-amino nitrogen atom, which was found to sit closely (3 4 Å) to the oxygen atom of the serine 119's hydroxyl group at the B C loop of CYP3A4 in an energetically favored orientation to form a strong hydrogen bond.

Configuration D represents the adsorption of O3 on the OC-substituted nanocomposite, while configuration E shows the favored orientation of O3 over the OT-substituted one.

It is found that the success of such C-6 amides in the series against influenza A NA was in part due to a match between the spatial arrangement of the two binding pockets and the favored orientation of the amide rotamer that featured a trans-relationship between the larger substituent and the pyran ring.

The most favored orientation for GABA in the binding site was with the ligand in the cleft among loops B−D.

Evaluating the MD structures of the preinsertion and insertion sites to consider translocation to the insertion site, we found that the adduct would need to rotate around α′ as the strand translocates; α′ adopts a value of 19.6 ± 12.3° (range of 8.7 30.4°) in the preinsertion site and 150.6 ± 45.0° (range of 98.1 160.9°) in the insertion site opposite dCTP in its 3′ favored orientation.

β-Alanine was found to dock in two almost equally favored orientations.

Although the loop could adopt multiple orientations that could bring these residues in close proximity, without this constraint Rosetta favored orientations that placed Asp495 more distant from the acceptor lysine.

Without correction, the missing wedge is the strongest feature in individual subtomograms and tends to bias the alignment of any two given subvolumes, favoring orientations with maximum density overlap as opposed to optimizing the overlap of matching structural features (Fig. 7).

Biases could have been generated by 1) preferred insertion of ISs in nonrandomly oriented sequences in the chromosome, 2) postinsertion selection favoring specific orientation, or 3) by transpososome interaction with an asymmetrical structure within the replication fork.

The results indicate that only the arc type discharges can effectively favor (101) orientation because they can generate the thermal stress large enough to cause (101) crystalline planes rotation while both the micro arc and luminescent spark cannot.