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These models and the corresponding analytical methods are favorable to optimize operating parameters and process design of HTC.
The comparison of the commonly used pulse feeding of methanol to P. pastoris cultures in shake flasks with the quasi continuous feeding clearly showed clearly that the commonly applied standard protocol is not favorable to optimize recombinant processes, mainly due to the long-term starvation phases.
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These systems overcome the drawbacks of traditional drug dosage form, and offer more effective and favorable methods to optimize drug delivery in optimum dose to specific sites or to prolong delivery duration.
Identifying responders to high-intensity PRT may allow for individually tailored lifestyle interventions in the future and development of cointerventions to optimize favorable body composition adaptations.
It would be an effective method to optimize the favorable shale lithofacies in guiding the exploration and development of shale gas.
To optimize conditions favorable for circadian rhythms in organoids, we doubled standard concentrations of EGF, Noggin and R-spondin in organoid medium and found a resulting increase in the amplitude of PER2 oscillations following serum shock (Fig. 4A).
The action taken in order to optimize the motivational level had a favorable influence upon the athlete's attitude.
Then their most energetically favorable minima in the positions near the pharmacophoric points were used to optimize the distances between pharmacophoric points.
The objective is to optimize the arrangement of tubes and find the most favorable geometries, in order to simultaneously maximize the rate of heat exchange while obtaining a minimum pressure loss.
When a new configuration of the ligand was generated, the search for the favorable binding was operated within a specified 3D box by the simulated annealing to optimize the purely spatial contacts as well as electrostatic interactions.
Among multiple attempts performed to optimize the binding conditions, we found two distinct methods that provided a favorable signal-to-noise profile (Fig. 1b & Additional file 1: Figure S2).
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