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After an employee's description of a sequence of events that he felt good about ("favorable") was completely explored, he was asked to tell of a different time when he felt the opposite ("unfavorable"); or, if he had first described an unfavorable sequence of events, he was asked about a favorable sequence.
The leaky scanning model dictates that if the first AUG is in a less favorable sequence context, then a fraction of 40S ribosomal subunits will bypass the first AUG and initiate translation at a downstream AUG.
This result highlights a dynamic process in which a transient preference of a nucleosome for occupying a thermodynamically favorable sequence is converted over time to an alternative chromatin conformation.
Tao et. al. [ 18] showed that WGA DNA has favorable sequence capture metrics when comparing to genomic DNA when adapting the NimbleGen capture array for use on the Illumina GA sequencing platform.
The majority of the currently annotated cases, including all based on FlyBase analysis (Table S3), are postulated due to the lack of an appropriately placed AUG codon; most are supported by assessment of conservation among Drosophila species or a favorable sequence context for translation initiation, but no additional experimental data.
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For example, 50% of the favorable sequences relate to achievement.
The length of the gray bars on the upper side of the transparent horizontal plane indicates the percentage of favorable sequences or events classified under each factor.
Our data suggest that the most favorable sequences for a T cell epitope-based vaccine are the 17 H1N1 T cell epitopes of the PB1, PB2, and M1 proteins (Table 4).
For the remaining 12 EST markers that could not be assigned to any contigs previously, the blast approach did not yield favorable sequences to be amplified.
We also observe that the majority of well-positioned in vivo nucleosomes do not occupy thermodynamically favorable sequences observed in vitro.
Gupta et al. [ 43] computed the percentages of dinucleotides from "nucleosome forming" and "nucleosome inhibiting" sequence sets and found an overrepresentation of several dinucleotides in "nucleosome inhibitory" and "nucleosome favorable" sequences, such as AC/GT and CC/GG, correspondingly.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com