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Acylhydrazone is a pharmacophore armed with favorable activity of antibiosis, anticancer and antivirus.
One of them, named J2, which possessed favorable activity, was obtained.
Compound 3a revealed favorable activity against tomato bacterial wilt in vitro compared with the commercial bactericide Kocide 3000.
In their research, several KN1022 (77) (Figure 2) derivatives with favorable activity were obtained, including 4- 4-methylphenoxy phenyl,4- 4-methylphenoxy phenylphenoxyphenyl.
Compared to natural superoxide dismutases, the artificial enzyme mimic exhibited favorable activity stability, indicating its promising applications in the in vivo long-term monitoring of superoxide anion.
Furthermore, phase II monotherapy trials in patients with advanced non-small cell lung cancer, ovarian cancer, and head and neck squamous cell cancer, respectively, show favorable activity compared with single-agent chemotherapy in similar patient populations.
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However, alkyl (3b d) or phenylamino carbonyl methyl compounds (7h i) did not give favorable activities because of their either low activity or high cytotoxicity.
The favorable activities of exenatide probably rely on the induction of a metabolic switch toward anaerobic glycolysis as well as increased production of lactate, two phenomena that can fuel the neurons of brains in which a valid cognitive reserve is still present.
In contrast to many existing micellar systems that have no favorable biological activity, our PEG5k Fmoc FTS2 conjugate well retained the biological activity of FTS.
Favorable market activity encourages lending, and borrowers then have sufficient reserves to facilitate their debts.
3,8-dibromo-7-hydroxy-4-methylchromen-2-one (DBC) analogues show favorable inhibitory activity targeting CK2α.
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