Exact(3)
In order to facilitate the process of safety analysis of an evolving software system, this paper presents an architectural approach that enhances the safety analysis by providing appropriate abstractions for modelling and analysing interactions between components, since faulty interactions are the usual cause of accidents.
Previous studies have suggested that the αB-R120G mutation causes DRM and cataracts due to faulty interactions between αB-crystallin and intermediate filament proteins such as vimentin [12], [31].
When a substantial number of chromosomes are engaged in these faulty interactions on both sister kinetochores, plus-end directed CENP-E-dependent forces exerted on stabilized lateral KT-MT attachments produce a net pulling force on centrosomes which disrupts the innermost centrosomal structure and generate multipolar spindles (Figure 8C).
Similar(57)
They are often caused by poorly designed back ends—services and databases on which the Website depends or by faulty interaction and communication between the back end and the front end.
Faulty interaction and communication in the health services was in this study the most important factor, followed by insufficient handling of the patients in primary and secondary care.
This compensatory recruitment is accompanied by faulty morphogenic interactions that reconstitute the VZ proliferative array and further disrupt the radial fibre network (Xie et al., 2002, 2009).
Instead, the pattern of substantial, progressive reduction of growth in the ablated pallium indicates that the initial defect introduced by the specific killing of GPT cells is amplified by subsequent, faulty cellular interactions.
Furthermore, faulty network network interactions could explain important facets of the bvFTD profile, especially since one function of the right frontoinsula may be to initiate organized switching between large-scale distributed networks (Sridharan et al. 2008).
An abnormally large fraction of Mia1p-MutNES4 cells (∼10%) showed the spindle assembly checkpoint (SAC) protein Mad2p present at kinetochores, indicative of faulty microtubule/kinetochore interaction and metaphase delay (Fig. 3C).
A faulty morphogenic interaction next takes place, most likely between the degenerated radial fibre network and the delayed replacement GPT neurons, which then fail to emit long projection axons (Xie et al., 2009).
A faulty trophic interaction then occurs between the impoverished terminal fields of long axonal projections and neurons in mature neocortex, which curtail the outgrowth and branching of their dendrites and local axonal collaterals (Adams et al., 1997; Xie et al., 2009).
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