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The gradual increase of kMTs may help turn off the spindle assembly checkpoint in normal conditions but can promote a faulty conformation (merotelic attachments) to evade the checkpoint.
In addition, the model explains why errors are more commonly found in the first meiotic division (meiosis I) than in mitosis and how a faulty conformation can evade the spindle assembly checkpoint, which may lead to a chromosome loss.
Moreover, the model explains why errors are more frequent in meiosis I than in mitosis and how a faulty conformation can evade the spindle assembly checkpoint by a gradual increase of the number of kMTs.
Similar(57)
Having detected faulty compliance, an explanation should be sought.
He had the conformation.
Faulty Towers?
Was it faulty?
Intelligence is inherently faulty.
"A faulty connection".
"I got faulty directions".
Faulty wiring.
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