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For example, in early embryogenesis, transcription of the antisense genes Tsix and Air determines the fate of expression of their sense partners Xist and Igf2r, respectively [ 3, 4].
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The fate of gene expression is determined by the changes in the downstream RNA sequence.
The proposed function of stress granules is the triage of mRNAs, dictating their fate for expression, degradation, or suppression in order to express the appropriate repertoire of proteins to reestablish homeostasis.
Focusing on the three TFs relevant for photoreceptor fate, their levels of expression were higher than the genes of the SUMO pathway, probably due to their central role in regulating genes for photoreceptor function and maintenance.
The fate of the mRNA expression of neuronal nitric oxide synthase (nNOS), protein expression of 3-nitro-tyrosine and concentration of nitrite level were analyzed.
WUS is expressed in the OC and is essential for the maintenance of SC fate and expression of CLV3 [5].
Canonical Wnt/ β-catenin signalling provides the master switch for determining the fate of HFs because expression of the Wnt inhibitor Dkk1 or lack of epidermal β-catenin resulted in the lack of induction of hair follicle growth [ 95, 96].
For instance, in the case of the development of the Drosophila embryo, forces resulting from internal motions of cells control cellular fate and expression of developmental genes.
This led to the hypothesis that S-cones are the 'default' fate, and expression of Nrl is required to switch on the molecular pathways that determine differentiation into the rod lineage (Swaroop et al., 2010), and that NRL and TR-β2 together determine different photoreceptor fates (Ng et al., 2011).
Therefore, as a key apoptotic protein that may decide the apoptotic fate of cells, Apaf-1 expression is tightly regulated.
NRG1-type NRG1-type IIIinstructive role on myelination and SC developlays, determining the ensheanhment fate of axons: instructive exproleion causes hypomyelination [ 33].
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