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They control the fate of cells.
In addition, they also play a strategic role in controlling the fate of cells through regulation of death pathways.
In such a context, the cooperation between p53 and NF-kappaB may be a critical factor in determining the fate of cells under inflammatory stress.
In the latest study, Tanaka's team employed a novel method for tracking the fate of cells from different tissues in a type of salamander called the axolotl.
To map the formation of these structures, we developed a broadly applicable, high resolution, recombinase-based method for mapping the fate of cells originating from coordinates defined by intersecting combinations of expressed genes.
The fate of cells is influenced by their microenvironment and many cell types undergo differentiation when stimulated by extracellular cues, such as soluble growth factors and the insoluble extracellular matrix (ECM).
Collectively, our study sheds light on the propensity of BclXL to form amyloid-like fibrils with important consequences on its mechanism of action in gauging the apoptotic fate of cells in health and disease.
from any decisions made, and because the decisions themselves will have to be socially acceptable in a way that does not apply to the fate of cells in tissue culture.
Any marked increase in levels of SUMO-conjugated proteins is therefore expected to have a major impact on the fate of cells.
Stem cell research is exciting precisely because the fate of cells turns out to be not determined by the genes.
Therefore, the use of nanomaterials presents an interesting opportunity to control the fate of cells for the development of biomedical technologies, such as cell therapies and tissue engineering.
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