Pou4f3 expression starts shortly after the hair cell fate is committed [54].
If cyclin D levels exceed a certain threshold, leading to hyperphosphorylation of the Rb protein, cell fate is committed to DNA synthesis and cell division.
Nevertheless, it can be displayed with RT-PCR that Oct91, but not Oct60 or Oct25, is activated specifically in the PGCs in Xenopus neurula embryos, when somatic fates are committed.
They went to sleep, presumably, on Sunday night as villains, having suffered the unfortunate fate of committing miscues at critical moments in big games.
In the play "Oedipus the King," the gods have cursed the tragic hero with a fate to commit two terrible crimes.
When she first returned to the tour in the summer of 2009, Clijsters said she would not look past her first three tournaments, unwilling as she was to tempt fate by committing herself too far into the future.
In summary, the global single-cell cDNA amplification microarray analysis of the 5- to 8-cell stage human embryos reveals that blastomere fate is not committed to ICM or TE.
Maybe another character accidentally killed the Fate Character, maybe they committed suicide.
Cell fate diversity mechanisms involving N-signalling are implicated in both lateral inhibition, an essential process in which one cell is selected from an equivalent cell group after a mutual exchange of signals, as well as cell fate induction, in which a competent cell is committed to its fate after unidirectional signalisation.
ChILP cells are defined as lineage−IL-7R+Flt-3−Integrin α4β7 +cellsId2high progenithatcells thavehave committed their fates to an ILC lineage (Klose et al., 2014) (Fig. 1).
Our results suggest that this general function of mTOR in promoting committed progenitor fates in a variety of tissues might reflect a strategy used by tissues to limit stem cell differentiation when nutrients are scarce and to renew growth by stimulating proliferation of rapidly dividing progenitors when nutrients become available.
