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The whole concept of fate, choice, and karmic retribution was first explored back in season one.
Is it due to an aberrant cell fate choice?
We also present evidence that it acts mainly as a regulator of ALC fate choice.
We further provide evidence that Dlk1 non-cell autonomously affects satellite cell fate choice between self-renewal and differentiation.
This observation suggests that epidermal IC cell fate choice might also be mediated by the Delta-Notch lateral inhibition mechanism.
We were interested in the molecular mechanism controlling the cell fate choice between epidermal ICs and epidermal SCs.
Neither ligand could induce Th1 or Th2 fate choice independently of cytokines or redirect cytokine-driven Th1 or Th2 development.
This study extends the mechanism of neuron-glial fate choice.
These results support the notion that BMP signaling regulates ISC/EB fate choice.
p53-centric models ascribe the cell fate choice to molecular events affecting the p53 molecule itself.
These results demonstrate that excessive BMP signaling favors ISC fate choice.
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