Sentence examples for fatal pathology from inspiring English sources
Moreover, conditional disruption of both IRP1 and IRP2 in the mouse intestine elicits severe fatal pathology in this organ [7].
Extracellular amyloid plaques (APs) and intraneuronal neurofibrillary tangles (NFTs) are two major hallmark lesions of this fatal pathology [ 13].
To this extent, cause of death from the death certificate provides a very partial basis for ascertaining the full extent of the impact of alcohol on potentially fatal pathologies.
Loss-of-function mutations in the gene encoding Foxp3 in mice and humans result in a lack of Treg and in fatal autoimmune pathology beginning at a very early age and affecting multiple organs [ 7].
IDPs perform a wide range of regulatory functions related to signal transduction, molecular recognition and molecular assembly (Ref. 3), and several have been implicated in fatal human pathologies (Ref. 4).
Overall, IFN-γ seemed to play a lethal role in the immunopathogenesis of TSS by inflicting fatal small bowel pathology.
A substantial TLR7 increase even caused fatal acute inflammatory pathology and extensive dendritic cell dysregulation [ 16].
Endothelial adhesion of parasitized red cells and endothelial activation are prominent features in the pathology of fatal malaria.
Although autopsy studies have improved understanding of cerebral malaria pathology in fatal cases, information about in vivo neurovascular pathogenesis is scarce because brain tissue is inaccessible in life.
These findings are consistent with a link between iRBC sequestration and intravascular and perivascular pathology in fatal pediatric CM, resulting in myelin damage, axonal injury, and breakdown of the BBB.
Finally, data obtained in a recent work performed on Malawian children are consistent with the proposed link between iRBCs sequestration and intravascular/perivascular pathology in fatal pediatric CM, resulting in myelin damage, axonal injury, and BBB breakdown; however, no Hz-laden monocyte extravasation was found [ 131].
