We proposed that if mtDNA deletion species have a replicative advantage over wild-type, based on a smaller size and faster replication time, larger mtDNA deletions would display the same replicative advantage over smaller mtDNA deletions.
On the other hand, too large h reduces the advantage of rarity, because rare replicator types are available in the (large) metabolic neighbourhoods of most other replicator types which are capable of faster replication, and thus the more common types outcompete the rare type and the system collapses.
S. Park and J. Ousterhout, "Exploiting Commutativity For Practical Fast Replication," Proc.
In gorgonian corals, also known as sea fans, warmer temperatures increase defenses, but also lead to faster replication for coral pathogens and changes in associated bacteria.
But despite such quality control efforts, the flexibility and adaptability that aided fast replication left the National Center with no effective way to manage or monitor the more than 2,000 sites worldwide.
The evolution of RNA viruses is governed by key features such as their fast replication, high per-base mutation rates, compacted genomes, poor robustness to mutation, stressed fitness tradeoffs, antagonistic epistasis, elevated particle counts, and strong transmission bottlenecks.
Moreover, the passaged viruses, unlike the parent virus, were able to readily infect mice and showed faster replication kinetics in tissue culture.
In Hackers and Painters: Big Ideas from the Computer Age, Graham explains how LISP made Viaweb more powerful, enabling fast replication of competitors' innovations.
The idea is this: if a group of similar genotypes with a faster replication rate occupies a "high and narrow peak" in the landscape of evolutionary fitness, while a different group of genotypes that replicates more slowly occupies a lower flatter, or broader, peak, then when mutation rates are high, the broadness of the lower peak can offset the height of the highest peak.
This diversity is a result of its fast replication cycle, with the generation of about 1010 virions every day, coupled with a high mutation rate of approximately 3 x 10−5 per nucleotide base per cycle of replication and recombinogenic properties of reverse transcriptase.
