Sentence examples for faster polymerase from inspiring English sources

This stems from the fact that a faster polymerase will have a greater error rate.

We expected that reverse polymerizing organisms, with the increased penalty for a spontaneous hydrolysis event, would have a greater selective pressure to evolve a faster polymerase holding all else constant.

Generally, we can state that tendency toward a faster polymerase indicates that the predominant evolutionary pressure is on reproduction rate, while a tendency toward slower polymerases indicates an increased importance of reducing the mutation rate.

In figure 2B, we can see that at simulation temperatures of 0.4 and 0.6 the reverse polymerizing organisms evolve to faster polymerase rates sooner than their forward polymerizing counterparts.

Since spontaneous hydrolysis of the triphosphate group occurs with a fixed rate constant at a constant temperature, a faster polymerase will be able to add more nucleotides to a growing chain between each such hydrolysis event, reducing the aggregate penalty for a given length of nucleic acid.

Moreover, the reverse polymerizing organisms at a simulation temperature of 0.4 appear to grow with identical kinetics to the forward polymerizing organisms at this temperature, showing that the penalty of a reverse polymerizing strategy can be compensated for by evolving a faster polymerase (as seen in fig. 2B).

At this point the selective pressure against faster polymerases resulting from the need to preserve generation to generation fidelity will, in effect, vanish.

The essence of this link is that there is an additional geometric constraint on erroneous nucleotide inclusions and that, in order to polymerize faster, polymerases must relax this constraint.

In the future, this reaction will be optimized with shortened denaturation/annealing steps and PCR-additives or fast polymerases, for example a KAPA2G Fast DNA Polymerase (Kapabiosystems, Wilmington, USA) with an elongation time of approximately 1 s/kb, thus leading to a significantly shortened overall reaction time.

It is the newer and faster tests, Polymerase Chain Reaction (P.C.R ., that are now being used in animal as well as human forensics.

The bacterial-type polymerases inherited by mitochondria from their α-proteobacterial ancestors might have been lost and replaced by faster phage polymerases to reduce DNA mutation rate [ 38] (Part 3, Section 9.7).