Exact(2)
In these cases a patient who requires transportation to hospital will require a patient-carrying ambulance to attend in addition to the fast responder.
While we required patients to have at least three data points in the first 6 months, the NLME approach used here can work with fewer data points such that a patient with only one assessment at month 6 could be classified as a fast responder if he or she has achieved BCR-ABL1 (IS) ≤ 0.1% (at least MMR) or a slow responder if his or her BCR-ABL1 levels are above 10%.
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Eighty-nine (35 %) patients were fast responders, 98 (38 %) were slow responders, and there were 71 (27%%) non-responders.
Please note that you're required to fit the above criteria to get in – only 20 fast responders will be allowed access to the private beta service.
Patients were classified into three groups according to their CRP ratio: fast responders if CRP ratio was ≤0.4; slow responders if CRP ratio was >0.4 and ≤0.8; and non-responders if CRP ratio was >0.8.
Dynamic modelling of collected time series data that provided the opportunity to identify slow, medium or fast responders as well as groups of subjects showing different response profiles, was also highlighted in the study.
Slow responders showed a non-significant increase on the odds of mortality in comparison with the fast responders (AOR = 1.5, 95% CI = 0.9 to 2.5; P = 0.124).
Slow responders showed a non-significant increase on the odds of mortality in comparison with the fast responders (OR = 1.5, CI95% = (0.9, 2.5), P = 0.124).
No responders had a significantly increase on the odds of mortality (OR = 2.5, CI95% = (1.6, 4.0), P < 0.001) when compared with fast responders.
No responders had a significant increase on the odds of death (OR = 2.5, CI95% = (1.6, 4.0), P < 0.001) when compared with fast responders.
Based upon the histopathology assessment after Eryf-AK treatment, the subjects were classified as fast responders (FR) versus slow-partial responders (PR) (Table S1).
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