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The large cluster of mouse Abp paralogues qualifies in three respects as genes that are rapidly evolving under strong positive selection, namely elevated KA/KS and a fast duplication rate, and now data showing rapid diversification of gene expression following duplication.
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For example, this algorithm may be used to identify strains with faster duplication or deletion rates.
The 914 revolutionized the workplace and brought its inventor fabulous wealth, but the father of fast document duplication preferred life in the slow lane.
This suggests very fast gene duplication after speciation.
This phenomenon, known as the Warburg effect, is thought to lend a metabolic advantage to highly proliferating cells when nutrient supply is not limiting, as it favours the synthesis of essential cellular components required for fast cell duplication.
Second, the rate of evolution in the younger fast-evolving duplications appears to be higher than in older duplications.
Column-store technology offers the same benefits for this action: fast and incremental duplication of a relation, scheduling, CQP adaptation, and an increase of the number of useful configurations.
These genes probably evolved at a fairly fast rate after duplication while the selective constraint was relaxed.
This result actually fits well with the previously described massive duplication and fast evolution of proteins involved in recently evolved BPs in primates and hominidae such as olfactory sensing (Niimura 2009) or immune and inflammatory responses (Eichler 2001; Rodriguez et al. 2012).
Finally, the rate of evolution in fast-evolving gene duplications appears to be elevated even for the oldest duplications in our dataset with δf appearing to have reached a plateau at δf ∼ 0.15 for gene duplications older than d s ∼ 0.2 (fig. 3 A).
We found that δis and δif are not significantly different even for gene duplications that have emerged recently (fig. 3 B), indicating that the slow copy evolves faster immediately after gene duplication and subsequently returns to the preduplication levels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com