Some of these ATXN1-interacting factors, in a dosage-dependent fashion, modify pathogenesis of SCA1 in mouse and fly models (7– 9, 11).
In the same fashion, ischemia modified albumin value lies in how it specifically denotes the presence of ischemia in the organism.
In the chiffon trenches, Ms. Kawakubo is the only designer who thinks like an artist, in that she creates fashion that modifies your view of something, be it women or an aspect of culture.
As a compass can be adjusted to find the quantitative measure of a variety of sizes and shapes, so our minds are able to fashion, adopt, modify and utilize both the literal and the symbolic ideas and concepts available to us for exploring and understanding the natural, social and conceptual worlds we inherit and extend.
During trafficking through the Golgi apparatus, crucial glycosyltransferases, SGK196, an O-mannose kinase (Yoshida-Moriguchi et al., 2013), and B4GAT1, a glucuronyltransferase (Praissman et al., 2014; Willer et al., 2014), act in a concerted and chronologically regulated fashion to modify the α-DG core protein.
This may reflect the intrinsic stochastic nature of gene regulation [ 45, 46], and raises the possibility that factors such as TOX3 that interact with DNA in a non-sequence specific fashion to modify chromatin [ 5], may alter the threshold of gene regulation and result in tumor cell heterogeneity that can then be acted upon by selective pressures.
The CLDA algorithm is difficult to implement in a real-time fashion, and then modified versions are presented to avoid the data whitening process.
Retinal grading was performed in a masked fashion using a modified version of the International Classification and Grading System for AMD.
Now that the FDA has lifted the clinical hold on the trial, the study can proceed in a slightly modified fashion.
After a lengthy investigation by the FDA and the Recombinant DNA Advisory Committee of the NIH, the trial was allowed to proceed in a slightly modified fashion.
