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Seroprevalence correlated significantly with farm density and the North-Atlantic Oscillation index, which describes temporal variations of meteorological conditions at the continental scale.
Counties varied in their mink farm density from 0 to 0.35 farms/100 km.
The farm was located in an isolated area of the province, with sparse hog farm density.
For the second scenario, the pig farm density map was added to the first three factors.
This is especially true in regions of high farm density which tend to suffer higher infection levels [ 81].
Also farm density per area of land [ 14] and animal manure application to soil are important [ 13].
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The highest seroprevalence values were obtained in areas with high farm densities and during years with cool and moist winters.
These differences may reflect different herd and farm densities, disease prevalence, and on farm management factors.
High pig-farm density in the neighborhood was identified as a risk factor in other studies as well [ 23].
To account for geographic distribution of flocks, France was divided into 9 sheep production areas according to sheep farming density and production patterns.
This area was chosen for the studies because a case of LA-MRSA infection was detected in 2008 [ 18], and because livestock farming is one of the main economical activities of this area, located in Lombardy, the region with the highest pig farming density in Italy [ 21].
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