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So far, increased expression of GFAP occurs constantly when spinal cord stem-like cells are proliferating following either spinal cord injuries [ 7, 23] or ALS [ 8].
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The UAS-line used in our study has not been employed for lifespan experiments so far and does not show increased expression of dnaJ-H, which has been shown to affect apoptosis control of Sir2 and may also interfere with Sir2 functions with regards to longevity [ 28].
Paradoxically, there was increased expression of DNAJC3.
Increased expression of adiponectin was also detected.
Differentiation increased expression of EPHB2 and EPHB3.
How this may induce increased expression is far from clear.
We have stated that U-CLL samples exhibit increased expression variability in many genes but we have not so far commented on whether specific functional categories are particularly affected by this increased variability of expression.
Only five displayed increased expression.
In experiments FRR of 5% and a FAR of 0.01% is obtained, without minutiae descriptors the FAR increased to 0.7%.
DSG significantly increased nuclear expression of ERβ.
It points at so far unappreciated increased complexity of gene expression control exceeding current paradigms.
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