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Far from correcting the distortion, such an approach would add further distortion from the likely complex high-dimensional multivariate relation between lesion volume (or any other reductive parameter) and the lesion pattern.
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Since the Gaussian assumption is not valid for high nonlinear systems, although the accuracy of the method is good in estimating the mean-square response, the probability distribution can be far from correct, particularly in the tail region.
I can tell by the mischievous glint in his eye that this answer is far from correct.
Almost three-quarters (72.3%) of age disparity estimates fell within 2 years of the true values, although a small minority of reports were far from correct.
His conclusion on intermittent fever being a variety of malaria was far from correct, yet Mahler did initiate brave comparisons of therapies among patients, albeit with bloodletting and dietary privations.
Indeed, incorrect answers close to the correct result are more likely to be experienced than incorrect answers far from the correct result, hence resulting in a stronger representation in verbal memory.
Wall Street's culture is notoriously competitive, impatient, abrasive -- about as far from politically correct as Mr. Bloomberg's offices are from City Hall's dowdy splendor.
The final translations generally give an average reader a solid understanding of the original meaning but are far from grammatically correct.
Presenter Wayne Sleep and the smart, humorous ballerina Monica Loughman have been far from politically correct in their handling of all the material.
Despite their name, Isis (or QSIS, to use the new coinage) militants are "far from the correct understanding of Islam", said Dar al-Ifta's head, Grand Mufti Shawki Allam.
It's far from politically correct theatre – there are a lot of sly laughs, but it's hard to escape the shadow over this play: the actors are the people Hitler wanted to exterminate.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com