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The highest score for the discovery of novel genes and degradation pathways has been achieved so far by functional screening of large clone libraries.
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The alcohol-generating FAR from B. mori was shown by functional expression to produce the pheromone bombykol from its precursor [ 25].
Thus far no functional data on this variant exist, hence the mechanism by which rs1485305 affects OPG expression or function is yet unknown.
However, thus far only a small number of duplicated gene families in vertebrate animals have been analyzed in detail by functional tests in vivo.
How far different functional families can diverge during evolution can be best represented by their power-law behavior.
"We in Amref recognise the important role that TBAs can play in communities that are far from functional health facilities.
This is about as attractive a thing as I could put in and far more functional than trees or bushes.
What do I mean by "functional medicine"?
The first two obvious conclusions are i) co-expression modules are by far more enriched in both functional terms (GO) and network structure than signatures are (82% versus 49%), and ii) both, co-expression modules and signatures are more enriched by functional terms than in network structure.
By contrast, little is known about the regulatory mechanisms of the Cyp26b1 gene expression, and thus far no functional RARE has been reported.
Thus far, no functional variants, explaining the effect on serum UA levels in GLUT9 gene, could be identified by Li et al. [18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com