The rarity of IIMs has precluded concordance studies in twins, but reports of multicase families support a familial predisposition [ 1].
Our findings provide further evidence of a familial predisposition to lung cancer and support the hypothesis that family history is a significant risk factor for the disease.
However, adoption and twin studies have shown that in addition to family environment, there is a strong genetic contribution to a familial predisposition for substance abuse [17], [18].
The positive antecedent of family history for epileptic events defined a TLE subgroup with familial predisposition for epileptic disorders.
This behavior, although often triggered by external factors, occurs in vulnerable individuals who have a neurobiological and often familial predisposition.
The familial predisposition to the disease is not well understood, although it is stronger in families with hypercholesterolemia and hypertension.
Because of their familial predisposition for the name Charles and because of the significance of Charlemagne in the family's history, modern historians have called them the Carolingian dynasty.
Familial predisposition predicted a poorer outcome.
Epidemiological studies found that there is a genetic and familial predisposition for migraine [5 7].
Recent reports suggest a familial predisposition to eosinophilic esophagitis (EE) and a link between Schatzki's rings and EE.
Stress, trauma, major surgeries, Helicobacter pylori infection, burns, familial predisposition, systemic diseases, and some drugs (NSAIDs and steroids) are other predisposing factors [5].
