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Imputation accuracy was estimated based on the comparison between imputed and known HD genotypes and was defined as the allelic imputation error rate, computed as the ratio between the number of falsely imputed alleles and the total number of imputed alleles [ 22].
Accuracy of imputation was measured by the ratio of the number of falsely imputed alleles to total number of imputed alleles, which will be referred to as allele error rate and the ratio of the number of falsely imputed genotypes to the total number of imputed genotypes, which will be referred to as genotype error rate, as well as the correlation between imputed and true genotypes.
This index represents the number of falsely imputed alleles divided by the total number of imputed alleles [ 14].
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Mann's court filing makes that very argument, saying the claims of academic fraud "falsely impute to Dr. Mann academic corruption, fraud, and deceit".
The statute says anyone who "speaks of and concerning any woman, married or unmarried, falsely and maliciously imputing to her a want of chastity" is committing a misdemeanor.
This can lead to the variance of the imputed data being artificially small, producing inappropriate standard errors, leading to inflated test statistics and falsely narrow confidence intervals and inappropriate p-values in any subsequent analysis [ 14, 15].
Missing loci were imputed using expectation maximisation.
Remaining missing values were imputed by K-nearest neighbours with the impute.knn function from the Impute R package.
Top panel, imputed Immunochip data; middle panel, imputed Immunochip data conditioned on the index SNP rs715285; bottom panel, imputed WTCCC2 GWAS data for psoriasis, excluding known PsA samples.
The rest was imputed rent.
Negligence may be imputed from one person to another.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com