Sentence examples for false interaction from inspiring English sources
We labeled an interaction 'T' (for possible True interaction) if it has two or more 'P' labels; otherwise it was labeled as 'F' (for possible False interaction).
Text-mining is not able to eliminate the selection of false interaction pairs; in the case of LAITOR (contained in the PESCADOR platform), the type 3 and 4 interactions can present genes with no association specified in the text [ 20].
All genes were mapped to the official gene symbol using HUGO Gene Nomenclature Committee (HGNC) [ 29] to avoid false interaction to same genes/proteins and the data curation was carried out using Microsoft Excel and Microsoft Access.
The simulation was repeated 100 times and summarized in Figure 2. As expected, the RV coefficient decreased as the false interaction rates increase, yet being significantly higher than the random predictions (P < 0.001, paired t-test).
The use of mixture design either within a well-defined range of the linear part on the dose-response curve or with equipotent doses saves experiments and reduces the possibility of false interaction terms in situations with dose additivity or response additivity.
This increase in space increases the number of interacting pharmacophores, thereby increasing the chance of false interactions.
We used only human interactions, eliminated the support_type = FALSE interactions and mapped by the HGNC column.
We performed the evaluation on simulated data, where false positive interactions are known, and on false interaction-imputed GEO data sets.
We found that for a set of simulated and false interaction-imputed experimental data sets, the utility of replication groups as described by Gayan et al. (2008) does not improve upon the direct scoring of SNP interactions.
A set of simulated and false interaction-imputed experimental SNP data sets were used to compare the inference of SNP-SNP interactions by means of replication groups to the standard approach where the entire data set was directly used to score all candidate SNP pairs.
True and false interactions were classified manually by experts.
