However, this repair mechanism is futile in the presence of high (F dUTP/dTTP ratios causing false nucleotide incorporation.
Many papers on tracking systems including (Bao et al., 2006) identify three types of errors: failure to incorporate an object, incorporation of a false-positive object and incorporation of an incorrect object in a given track.
Thus, high weights can lead to the incorporation of false interactions in the case of inaccurate PKIs (MEN more prone than BBSR), and impair performance on the leave-out set (as seen in BBSR).
In vitro studies suggest that inhibition of ribonucleotide reductase by HU (Choi et al. 2007) interferes with conversion of 5-azacytidine to 5-aza-2′-deoxycytidine, thereby decreasing incorporation of the false nucleotide into DNA and diminishing its hypomethylating effect.
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To assess the effectiveness of prior knowledge incorporation and robustness of kDDN when false positive edges were present in prior knowledge, we examined the network inference precision and recall of the overall network and the differential network at different levels of false positive rate in the prior knowledge.
Indeed, a US study suggests that parents have a high tolerance to false positive newborn screening results [ 54] and the incorporation of the loss in quality of life associated with false positive test results did not noticeably increase the ICER [ 23].
Although proteins travel in the cell and can coexist in multiple compartments, incorporation of subcellular localization data helps eliminate many false negative interactions.
Incorporation of the PCR internal standard allows identification of false-negative samples that may contain Taq polymerase inhibitors.
Because the presence of the Cbf1 motif in a promoter was predicted by in silico analysis, incorporation of the phylogenetic conservation information can reduce the possibility of false positive.
