Its usage may have serious implications for patients and society by creating false hope, compounding adverse effects, and delaying CM treatment and utilisation of resources that could be channelled into evidenced-based practices.
37 We found no information on possible adverse effects of false positive or false negative test results and labelling and on behavioural changes postpartum.
Several studies have shown that women with normal results after mammography screening experience no important negative psychological consequences, whereas recall because of a false-positive mammogram causes adverse emotional, physical and social effects (Lerman et al, 1991; Cockburn et al, 1994; Sutton et al, 1995; Gilbert et al, 1998).
The level aimed for depends on the intended application, particularly on the goal of testing, the medical, psychological and financial burden of the disease, the availability of (preventive) treatment and the adverse effects of false-positive and false-negative test results.
Thus, to suppress the adverse influence of false detection, we used the strategy of selecting stable segments of the tongue body contour.
He also requested that Gibson Dunn attorney Randy Mastro, who led the investigation, remove his "demonstrably false legal assertion that an adverse inference can be drawn from Mr. Stepien's invocation of the Fifth Amendment in response to the subpoena of a legislative committee".
Bias that either masks teratogenicity or creates false appearance thereof, may have adverse consequences for the health of the child and the mother.
However, setting the cutoff to achieve very high sensitivity can result in many false positives, which could have adverse consequences to the population being screened (e.g., unnecessary travel delays, missed work) and increase the workload of staff who are conducting the screening.
In the case of surveillance for bioterrorism attacks, the benefits of early detection must be balanced by the adverse effects of false positive alarms, an aspect of surveillance systems that supports the use of weighted ROC curve analysis in their evaluation.
Finally, the findings from the Diagnostic Test Accuracy component of the study will help to improve the surveillance tools and the related processes in order to minimise the adverse impact of false negative results from surveillance, and to ensure optimal outcomes for children who are identified as being at risk of a developmental disorder.
