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Each promoter flanks the TSS of a transcript and regulates transcription of exons falling downstream of its genomic position, which may be within an intron of the locus.
Indeed, using multiple and distinct chemical inducers of a full or partial stumpy-like phenotype would allow iterative RNAi screens, with resistance phenotypes being observed only for molecules falling downstream of where the compounds act on the signaling pathway.
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(1 Nucleotide position in the full alignment of F6854, F6900, J0161 and J2818; this alignment is available at (2 Arrows indicate direction of genes in the chromosome, e.g. 0351 → 0352 means that the polymorphism falls downstream to LMOf6854_0351 and upstream to LMOf6854_0352.
Alternative boundaries were slightly but not significantly more likely to fall downstream of the JEC21 boundary ('+' changes Table 1; 16/25 in all; P = 0.12) for both 5' changes (4/5) and 3' changes (12/20).
Ten feet away from my hammock, the coffee-coloured waters of the now-swollen r¿o San Juan rushed clumps of fallen vegetation downstream.
Note: Updates will flow downstream.
With arch dams it is convenient to construct gated openings in the shell structure at some distance below the crest of the dam, ensuring that the discharging jets fall well clear downstream.
It can be inferred from Fig. 2 (a) that pH exhibit a significant difference among the sampling sites, where pH at outfall and downstream fell under the permissible limit (6.5 7.5) while at the other sampling sites exceeded the guidelines.
Strand information was not included in assigning target genes, so a peak could fall upstream or downstream of the TSS of its assigned target gene.
Low MCS scores 1 month after ED discharge were also not strongly associated with downstream falls or hospitalizations.
Only the promotes in the upstream cluster of H3K9ac are more likely to fall into the downstream, instead of the upstream cluster of RNA polymerase II.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com