Of note, the PD-1+ expression levels of the input samples were low (13.0-36.3% of CD4+; 3.1-14.7% of CD8+) but fell within the broad range reported for CLL PBMCs, which spans and encompasses the healthy donor range (Brusa et al., 2013; Gassner et al., 2014; Nunes et al., 2012; Riches et al., 2013; te Raa et al., 2014).
For iPTH we used a cut off of 300 pg/mL, the upper limit of the range recommended by KDOQI [ 8]: this also falls within the broader range suggested by KDIGO [ 12].
The overall yield in heterologous GFP production via chimeric yeast VLP expression falls within the broad-range levels of GFP fusion protein production which has been shown to range over 3 orders of magnitude, from 4 µg/liter to 4 mg/liter yeast cell culture [36], [37].
"Our costs are within the broad range of costs that the EPA produces," said Paul Bachman, who directly oversaw the study.
We found a concordance rate (72%) which falls within this broad range.
The scaling holds for intervals that fall within a broad range determined by the autocorrelation structure of the stimulus but does break down eventually (see Supplemental Experimental Procedures S1.11 and Figure S1 available online).
I found the offenders to be a heterogeneous group, and the crimes themselves fall within a broad range — some brutalized their victims after sexually assaulting them, others did not brutalize them, some others were cases of both assault and homicide.
A social networking app called Meal Snap allows users to get nutritional breakdowns by taking pictures of their food, though the calorie estimates often fall within a broad range.
The genes we identified (see Additional file 1), which fall within a broad range of functional categories, appeared to provide the molecular basis for its pleiotropic effects.
Whilst ~20% of patients with diabetes and lower leg ulcers had total PC levels lower than the normal range, the mean total PC level (96%) of this group fell within the broad normal range (70%–180%).
