Sentence examples for faithfully regulate from inspiring English sources
Thus, the conclusion that these truncated p63 proteins, if they exist, can faithfully regulate epidermal and hair follicle morphogenesis, is not supported by the data.
If faithfully regulated in the mice, this transgene would be expressed beginning at embryonic day (E) 6.5 in the epiblast, at ∼E8.5 in embryonic and extra-embryonic mesoderm (37), and throughout the CNS by E10 (38).
"These two defendants exploited the trust placed in the transfer agency to faithfully and honestly carry out its duties to regulate the issuance and cancellation of company stock," said John S. Gordon, the United States attorney for the Central District of California.
Fz2 faithfully localizes to the NMJ despite reduced Ank2 levels (Fig. 5K; supplementary material Fig. S2G), again arguing that Ank2 does not simply regulate the localization of Wg-Fz2-Gαo signaling components.
Our controls show that we faithfully identified region-specific genes regulated by the Wnt/β-catenin and the Hh pathways by genetically depleting head or GZ by RNAi treatments.
Notably, Bambi, a BMP/Activin membrane bound receptor inhibitor [48], and Syt7 (synaptotagmin VII), a calcium sensor protein that regulates exocytosis [49], follow faithfully the activation pattern of Smad2/3 in all time points in both Dox/SB experiments (Figure 6C and Table S6) and under CHX (Figure 6A and 6B) suggesting that they are direct targets.
Therefore, DMRs do not appear to be especially sensitive to early dietary manipulations, and it might be that mechanisms that faithfully maintain methylation at DMRs have evolved to help ensure that imprinted genes are normally regulated within quite narrow boundaries and that imprinted genes are not especially plastic to nutritional or environmental states.
Because the transformation status of a cell regulates exosome secretion [47], and thus possibly exosomal miRNA release, we sought to identify a miRNA that faithfully reflects exosomal abundance in order to quantify selective miRNA release into vesicles.
