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These experiments verify that the 384 well version of the yeast-based Caspase-dependent reporter gene assay faithfully indicates the activity of an inhibitory compound, thus fulfilling one of the prerequisites for developing HTS assays.
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Interestingly, PER DNA transcripts can become catalytic themselves, being able to cut an arbitrary target RNA, become fluorescently labeled probes that amplify the presence of a particular molecular stimulus, or "molecular recorders" that faithfully indicate the order in which certain molecular signals appear in their environments.
Yet, the amount of 5mC-positive ONL cells reflected the amount of TUNEL-positive cells faithfully, again indicating that the DNA hypermethylation was somehow related to the degeneration.
The absence of significant differences between the empirical and the simulated distributions indicates that the model faithfully reproduces reality.
This indicates that the AC/AE model faithfully recapitulates early heart development (Fig. S3).
This indicates that ZFN-induced mutations were faithfully transmitted through the germ line.
This likely indicates that the gufm1 model does not faithfully reproduce the geomagnetic field evolution in Western Europe between the late sixteenth century and the seventeenth century and only does so from approximately 1675 onward (Fig. 3).
This indicates that older participants represent young age more faithfully, leading to the youngest numerical age judgments in younger and older validators (a similar trend applies for old age in the last two ranks).
The 50% efficiency of the infection in the first passage indicates that the annealing protocol might not yet faithfully mimic the interaction of rPrP with a co-factor for generating authentic PrPSc in vitro.
The development of new biomedical models of disease in large mammals indicates that they recapitulate the disease in many aspects more faithfully than rodents (Aigner et al., 2010; Luo et al., 2012).
An overall strong cophenetic correlation coefficient of 0.70 based on morphological characteristics (Table S1) was obtained, indicating a faithfully constructed dendrogram.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com