San Franciscans have historically considered their city to be laissez-faire and open-minded, which is probably why homosexuals have felt comfortable there.
To investigate the relationship of these read clusters with higher-order chromatin organization we downloaded annotation tracks that give signal strength for stable nucleosome cores (MNase-seq) and open chromatin regions (FAIRE-seq) in the lymphoblast cell-line (Gm12878) available through the ENCODE project [ 59, 63].
For example, Waki et al. performed computational motif analysis of the adipocyte-specific FAIRE peaks (open chromatin sites) and discovered an enrichment of a binding motif for nuclear family I (NFI) transcription factors [ 12].
We investigated four adaptation strategies that encompassed laissez-faire, larger sewer pipes, local infiltration units, and open drainage system in the urban green structure.
Similar percentages of human genome, 11.76%, 11.97% and 13.87%, comprise DNA binding sites of protein by ChIP-seq and open chromatin regions by DNase-seq and FAIRE-seq, respectively.
This demonstrates that comparative transcriptomics (present study) and open chromatin profiling using ATAC-seq and FAIRE-seq (Davie et al., 2015) are suitable complementary approaches for mining the key regulatory TFs responsible for controlling complex in vivo processes, such as tumorigenesis.
It's been a form of laisser faire and laxity.
What is happening is that growth is laissez faire and disconnected from place.
This paper explores the laissez faire and discretionary traditions adopted for development control in Central Sydney over the last half century.
"The EU's laissez faire open border policy was part of a long list of administrative blunders in dealing with the migration crisis," said Amed Khan, a longtime aide to Bill Clinton, during a phone conversation.
Patterns for histone density and FAIRE were consistent with open, nucleosome-poor and closed, nucleosome-rich chromatin states for expressed and non-expressed genes respectively (Supplementary Figure S5).
